Definition

To utterly demolish or defeat someone in an absurdly over-the-top, hyperkinetic manner—a deep-cut reference to Homestar Runner's alternate dimension where everything is cranked up to ridiculous levels.

Example Usage

I totally 20X6'd him in the fighting game with that impossible combo move.

Source: Urban Dictionary (https://www.urbandictionary.com/define.php?term=20X6%27d&defid=615870)

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